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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $63.75 | Total: $318.75 |
| 1 | 10 | $54.00 | Total: $540.00 |
| 1 | 25 | $45.75 | Total: $1,143.75 |
| 1 | 50 | $39.00 | Total: $1,950.00 |
| 1 | 100 | $33.75 | Total: $3,375.00 |
Overview
BAY-85-8501 is a selective, reversible, and potent inhibitor of Human Neutrophil Elastase (HNE) with an IC50 of 65 pM.
Chemical Properties
| Molecular Formula | C22H17F3N4O3S |
| Molecular Weight | 474.46 |
| CAS Numbers | 1161921-82-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1[C@@H](C(C#N)=C(C)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1S(C)(=O)=O)C#N |
Storage and Handling
0C Short Term, -20C Long Term
References
Von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10[7] 1163-73.