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Autogramin-1
AOB13196
CAS: 2375541-73-2
Chemical Name: 4-Benzhydrylidene-1,1-dimethylpiperidin-1-ium methyl sulfate
1973 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $50.15 | Total: $250.75 |
| 1 | 10 | $42.48 | Total: $424.80 |
| 1 | 25 | $35.99 | Total: $899.75 |
| 1 | 50 | $30.68 | Total: $1,534.00 |
| 1 | 100 | $26.55 | Total: $2,655.00 |
Overview
Novel autophagy inhibitor, selectively targeting cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A), and directly competing with cholesterol binding to the GRAMD1A StART domain
Chemical Properties
| Molecular Formula | C23H27N5O5S |
| Molecular Weight | 485.56 |
| CAS Numbers | 2375541-73-2 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-Benzhydrylidene-1,1-dimethylpiperidin-1-ium methyl sulfate |
| SMILES Code | O=C(N1)N(CCC)C(C2=C1C=C(C(NC3=NC(CCN(C(OC(C)(C)C)=O)C4)=C4S3)=O)C=C2)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.
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