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CaspPro
AOB5477
CAS: 1060253-24-8
Chemical Name: C2; 3-Cyclopropyl-6-[4-(2-phenyl-ethenesulfonyl)-piperazin-1-yl]-[1,2,4]triazolo[4,3-b]pyridazine
49 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $109.65 | Total: $548.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 100 | $58.05 | Total: $5,805.00 |
Overview
Novel selective caspase 8 activator, potentiating TRAIL-induced cell death
Chemical Properties
| Molecular Formula | C20H22N6O2S |
| Molecular Weight | 410.49 |
| CAS Numbers | 1060253-24-8 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-Cyclopropyl-6-[4-(2-phenyl-ethenesulfonyl)-piperazin-1-yl]-[1,2,4]triazolo[4,3-b]pyridazine |
| InChl Key | JDOAIOBLXZJZBL-XNTDXEJSSA-N |
| InChl Code | InChI=1S/C20H22N6O2S/c27-29(28,15-10-16-4-2-1-3-5-16)25-13-11-24(12-14-25)19-9-8-18-21-22-20(17-6-7-17)26(18)23-19/h1-5,8-10,15,17H,6-7,11-14H2/b15-10+ |
| SMILES Code | O=S(N1CCN(C2=NN3C(C=C2)=NN=C3C4CC4)CC1)(/C=C/C5=CC=CC=C5)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
CaspPro; Casp Pro; Casp-Pro; C2; C-2; C 2
References
1) Octavian B. et al., A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death, Scientific Reports volume 5, Article number: 9893 (2015)