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DRAinh-A250
AOB36412
CAS: 858747-13-4
Chemical Name: 2-(7-((3-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid
250 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Novel SLC26A3 inhibitor, blocking colonic fluid absorption and reducing constipation
Chemical Properties
| Molecular Formula | C20H17BrO5 |
| Molecular Weight | 417.26 |
| CAS Numbers | 858747-13-4 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(7-((3-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid |
| InChl Key | STHJGDCGBDTTHP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H17BrO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23) |
| SMILES Code | O=C(O)CC(C1=O)=C(C)C2=C(O1)C(C)=C(OCC3=CC=CC(Br)=C3)C=C2 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
DRAinhA250; DRAinh A250; DRAinh-A250
References
1) Haggie PM, Cil O, Lee S, Tan JA, Rivera AA, Phuan PW, Verkman AS. SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation. JCI Insight. 2018 Jul 26;3(14). pii: 121370. doi: 10.1172/jci.insight.121370. [Epub ahead of print] PubMed PMID: 30046015; PubMed Central PMCID: PMC6124422.