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BC-1471
AOB36470
CAS: 896683-78-6
Chemical Name: N-(Furan-2-ylmethyl)-2-((6-morpholino-4-oxo-3-phenethyl-3,4-dihydroquinazolin-2-yl)thio)acetamide
AOBIOUS launched this product in 2020
CITATIONS - Publications That Use AOBIOUS Product
982 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Overview
Novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism
Chemical Properties
| Molecular Formula | C27H28N4O4S |
| Molecular Weight | 504.61 |
| CAS Numbers | 896683-78-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-(Furan-2-ylmethyl)-2-((6-morpholino-4-oxo-3-phenethyl-3,4-dihydroquinazolin-2-yl)thio)acetamide |
| InChl Key | GJKRCJKXXVVAMV-JOCHJYFZSA-N |
| InChl Code | InChI=1S/C27H32N4O4S/c32-25(28-18-22-7-4-14-35-22)19-36-27-29-24-9-8-21(30-12-15-34-16-13-30)17-23(24)26(33)31(27)11-10-20-5-2-1-3-6-20/h1-3,5-6,8-9,17,22H,4,7,10-16,18-19H2,(H,28,32)/t22-/m1/s1 |
| SMILES Code | O=C(NC[C@@H]1OCCC1)CSC(N2CCC3=CC=CC=C3)=NC4=C(C=C(N5CCOCC5)C=C4)C2=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
BC1471, BC 1471
References
1) JS Bednash et al., Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity, Nat Commun. 2017; 8: 15203.
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