Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
Overview
KP-457 is a specific inhibitor of a disintegrin-metalloproteinase 17 (ADAM17) and a TNF? converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).
Chemical Properties
| Molecular Formula | C21H24N2O7S2 |
| Molecular Weight | 480.55 |
| CAS Numbers | 1365803-52-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=CN(O)C(C1=CC=C(C=C1)CNS(=O)(=O)C)CS(=O)(=O)C2=CC=C(OCC#CC)C=C2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hirata S, et al. Stem Cells Transl Med. 2017 Mar;6[3] 720-730.