Ansamitocin p-3

Ansamitocin p-3

AT22262

CAS 66584-72-3

More details

1000 Items

$55.90

$55.90 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $36.55 Total: $182.75
110 $30.96 Total: $309.60
125 $26.23 Total: $655.75
150 $22.36 Total: $1,118.00
1100 $19.35 Total: $1,935.00

Overview

Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 ?M for tubulin polymerization.

Chemical Properties

Molecular FormulaC32H43ClN2O9
Molecular Weight635.14
CAS Numbers66584-72-3
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(CC(C)=CC=C[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)C(C)C

Storage and Handling

0C Short Term, -20C Long Term

References

Kiso T, et al. Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss. Antimicrob Agents Chemother. 2004 May;48[5] 1739-48