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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion Matrigel model. ARP-100 has low inhibitory activity against MMP-1 (>50 ?M), MMP-3 (4.5 ?M), MMP-7 (>50 ?M) and MMP-9 (0.2 ?M)[1][2].
Chemical Properties
| Molecular Formula | C17H20N2O5S |
| Molecular Weight | 364.42 |
| CAS Numbers | 704888-90-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Rossello A, et al. New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A [MMP-2]. Bioorg Med Chem. 2004 May 1;12[9] 2441-50.