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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $155.55 | Total: $777.75 |
| 1 | 10 | $131.76 | Total: $1,317.60 |
| 1 | 25 | $111.63 | Total: $2,790.75 |
| 1 | 50 | $95.16 | Total: $4,758.00 |
| 1 | 100 | $82.35 | Total: $8,235.00 |
Overview
BPHA (MMP-2MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000 and 795 nM, respectively).BPHA has anti-angiogenic and BPHA has anti-angiogenic and anti-tumor activities.
Chemical Properties
| Molecular Formula | C21H20N2O4S |
| Molecular Weight | 396.46 |
| CAS Numbers | 193807-60-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | S(N[C@H](CC1=CC=CC=C1)C(NO)=O)(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Maekawa R, et al. Correlation of antiangiogenic and antitumor efficacy of N-biphenyl sulfonyl-phenylalanine hydroxiamic acid [BPHA], an orally-active, selective matrix metalloproteinase inhibitor. Cancer Res. 1999;59[6] 1231-1235.