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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.90 | Total: $144.50 |
| 1 | 10 | $24.48 | Total: $244.80 |
| 1 | 25 | $20.74 | Total: $518.50 |
| 1 | 50 | $17.68 | Total: $884.00 |
| 1 | 100 | $15.30 | Total: $1,530.00 |
Overview
Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
Chemical Properties
| Molecular Formula | C15H19N3O2 |
| Molecular Weight | 273.33 |
| CAS Numbers | 1642288-47-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Kawas R F , Anderson R L , Ingle S R B , et al. A small molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle[J]. Journal of Biological Chemistry, 2017, 292[40] jbc.M117.776815.