Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
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- TNF Receptors
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- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading to mitotic blockade and apoptosis.
Chemical Properties
| Molecular Formula | C22H23N3O3S |
| Molecular Weight | 409.5 |
| CAS Numbers | 2366260-33-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(S(=O)(=O)C1=CC=C(C)C=C1)C2=CC(C(NCC=3C=CC(C)=NC3)=O)=CC=C2C |
Storage and Handling
0C Short Term, -20C Long Term
References
Lin S, et al. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J Med Chem. 2022;65[24] 16372-16391.