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XX-650-23
AOB31725
CAS: 117739-40-9
Chemical Name: N-(4-Cyanophenyl)-3-hydroxy-2-naphthamide
987 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Overview
Novel inhibitor of CREB (cAMP Response Element Binding protein)
Chemical Properties
| Molecular Formula | C18H12N2O2 |
| Molecular Weight | 288.31 |
| CAS Numbers | 117739-40-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Shipping Condition | XX-650-23; XX 650 23; XX65023 |
| IUPAC/Chemical Name | DRBIYQSSEMTUJQ-UHFFFAOYSA-N |
| InChl Key | InChI=1S/C18H12N2O2/c19-11-12-5-7-15(8-6-12)20-18(22)16-9-13-3-1-2-4-14(13)10-17(16)21/h1-10,21H,(H,20,22) |
| InChl Code | O=C(NC1=CC=C(C#N)C=C1)C2=C(O)C=C3C=CC=CC3=C2 |
| SMILES Code | 1) Chae HD, Cox N, Dahl GV, Lacayo NJ, Davis KL, Capolicchio S, Smith M, Sakamoto KM. Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways. Oncotarget. 2017 Dec 31;9(4):4301-4317. 2) François S, Sen N, Mitton B, Xiao X, Sakamoto KM, Arvin A. Varicella-Zoster Virus Activates CREB, and Inhibition of the pCREB-p300/CBP Interaction Inhibits Viral Replication In Vitro and Skin Pathogenesis In Vivo. J Virol. 2016 Sep 12;90(19):8686-97. doi: 10.1128/JVI.00920-16. Print 2016 Oct 1. PubMed PMID: 27440893; PubMed Central PMCID: PMC5021407. |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
N-(4-Cyanophenyl)-3-hydroxy-2-naphthamide
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