Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $97.75 | Total: $488.75 |
| 1 | 10 | $82.80 | Total: $828.00 |
| 1 | 25 | $70.15 | Total: $1,753.75 |
| 1 | 50 | $59.80 | Total: $2,990.00 |
| 1 | 100 | $51.75 | Total: $5,175.00 |
Overview
Eliapixant (BAY 1817080) (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
Chemical Properties
| Molecular Formula | C22H21F3N4O3S |
| Molecular Weight | 478.49 |
| CAS Numbers | 1948229-21-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@@H](NC(=O)c1cc(O[C@@H]2CCOC2)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Spinaci A, et, al. P2X3 Receptor Ligands Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12 653561.