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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Overview
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X23 heterotrimeric receptors.
Chemical Properties
| Molecular Formula | C14H19N5O4S |
| Molecular Weight | 353.4 |
| CAS Numbers | 1015787-98-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Anthony P. Ford, et al. The therapeutic promise of ATP antagonism at P2X3 receptors in respiratory and urological disorders. Front Cell Neurosci. 2013; 7 267.