Categories
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Overview
BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels.
Chemical Properties
| Molecular Formula | C20H17ClN2O4S |
| Molecular Weight | 416.88 |
| CAS Numbers | 2055602-83-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2)ccc1Oc1cccc(Cl)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Werner S, et al. Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-[3-Chlorophenoxy]-3-sulfamoylphenyl]-2-phenylacetamide [BAY-1797] and Structure-Guided Amelioration of Its CYP3A4 Induction Profile. J Med Chem. 2019 Dec 26;62[24] 11194-11217.