Deserpidine

Deserpidine

AT8270

CAS 131-01-1

More details

1000 Items

$61.10

$61.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $39.95 Total: $199.75
110 $33.84 Total: $338.40
125 $28.67 Total: $716.75
150 $24.44 Total: $1,222.00
1100 $21.15 Total: $2,115.00

Overview

Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.Deserpidine's mechanism of action is through inhibition of the ATPMg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.

Chemical Properties

Molecular FormulaC32H38N2O8
Molecular Weight578.65
CAS Numbers131-01-1
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Storage and Handling

0C Short Term, -20C Long Term

References

Varchi G, et al. Synthesis of deserpidine from reserpine. J Nat Prod. 2005 Nov;68[11] 1629-31.