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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $62.90 | Total: $314.50 |
| 1 | 10 | $53.28 | Total: $532.80 |
| 1 | 25 | $45.14 | Total: $1,128.50 |
| 1 | 50 | $38.48 | Total: $1,924.00 |
| 1 | 100 | $33.30 | Total: $3,330.00 |
Overview
MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM.
Chemical Properties
| Molecular Formula | C22H24N6O |
| Molecular Weight | 388.47 |
| CAS Numbers | 2654743-22-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(C#N)c1C |
Storage and Handling
0C Short Term, -20C Long Term
References
Ketcham JM, et al. Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1 KRAS Protein-Protein Interaction. J Med Chem. 2022 Jul 28;65[14] 9678-9690.