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Overview
Methyl-?-cyclodextrin (Methyl-beta-cyclodextrin) is a macrocyclic compound utilized as a solubilizer for hydrophobic substances in biological studies, and serves as a lipid raft inhibitor with cholesterol-lowering and potential antitumor activities.
Chemical Properties
| Molecular Formula | C54H94O35 |
| Molecular Weight | 1310(Average) |
| CAS Numbers | 128446-36-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | |
| InChl Key | |
| InChl Code | |
| SMILES Code | COCC1OC2OC3C(COC)OC(OC4C(COC)OC(OC5C(COC)OC(OC6C(COC)OC(OC7C(COC)OC(OC8C(COC)OC(OC1C(O)C2OC)C(OC)C8O)C(OC)C7O)C(OC)C6O)C(OC)C5O)C(OC)C4O)C(OC)C3O |
Storage and Handling
0C Short Term, -20C Long Term
Synonyms
References
Gotoh K, et al. The antitumor effects of methyl-?-cyclodextrin against primary effusion lymphoma via the depletion of cholesterol from lipid rafts. Biochem Biophys Res Commun. 2014 Dec 12;455[3-4] 285-9.