Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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Overview
ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-?B and TNF-? secretion from LPS-treated macrophages.
Chemical Properties
| Molecular Formula | C12H13NO4 |
| Molecular Weight | 235.24 |
| CAS Numbers | 478336-92-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC(=O)CC1CC(=NO1)c1ccc(O)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Xu L, et al. Drug Discov Today. 2013 Jun;18[11-12] 592-600.