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Overview
2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechanism of 2'-O-Methyl-5-iodouridine is dependent on the inhibition of DNA synthesis and induction of apoptosis.
Chemical Properties
| Molecular Formula | C10H13IN2O6 |
| Molecular Weight | 384.12 |
| CAS Numbers | 34218-84-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(I)=C2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Gophane DB, et al. A semi-rigid isoindoline-derived nitroxide spin label for RNA. Org Biomol Chem. 2018;16[5] 816-824.