Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
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- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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Overview
TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a trialkylphosphine that selectively reduces proteolysis. TCEP hydrochloride is a non-thiol-reducing agent that promotes the binding of NF-?B-DNA.
Chemical Properties
| Molecular Formula | C9H16ClO6P |
| Molecular Weight | 286.65 |
| CAS Numbers | 51805-45-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.OC(=O)CCP(CCC(O)=O)CCC(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Burns J A, et al. Selective reduction of disulfides by tris[2-carboxyethyl]phosphine[J]. Journal of Organic Chemistry, 1991, 22[39] 2648-2650.