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Overview
Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory properties that promotes the polarization of M1 to M2 macrophages by reducing the secretion of pro-inflammatory cytokines, and is utilized in research on keloids and rheumatoid arthritis.
Chemical Properties
| Molecular Formula | C22H29FNaO8P |
| Molecular Weight | 494.42 |
| CAS Numbers | 151-73-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [Na+].[Na+].C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP([O-])([O-])=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Wang L, et al. Determination of betamethasone disodium phosphate in the in vitro media of PLGA microspheres by high-performance liquid chromatography. J Pharm Biomed Anal. 2002;28[3-4] 629-635.