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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK46 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
Chemical Properties
| Molecular Formula | C17H18N2O2 |
| Molecular Weight | 282.34 |
| CAS Numbers | 1460286-21-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ccc2n1cc([nH]c2=O)-c1ccc(cc1)C(C)(C)O |
Storage and Handling
0C Short Term, -20C Long Term
References
Menon M, et al. A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK46 inhibitors. Sci Rep. 2019 Jan 17;9[1] 201.