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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $72.25 | Total: $361.25 |
| 1 | 10 | $61.20 | Total: $612.00 |
| 1 | 25 | $51.85 | Total: $1,296.25 |
| 1 | 50 | $44.20 | Total: $2,210.00 |
| 1 | 100 | $38.25 | Total: $3,825.00 |
Overview
AG-10 (Acoramidis) is an orally active and selective kinetic stabilizer of TTR (transthyretin). AG-10 exhibits activity for WT and V122I-TTR. AG-10 is used in the study of transthyretin amyloidosis.
Chemical Properties
| Molecular Formula | C15H17FN2O3 |
| Molecular Weight | 292.31 |
| CAS Numbers | 1446711-81-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(CCCC=1C(C)=NNC1C)C2=CC(C(O)=O)=CC=C2F |
Storage and Handling
0C Short Term, -20C Long Term
References
Sravan C Penchala, et al. AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. Proc Natl Acad Sci U S A. 2013 Jun 11;110[24] 9992-7.