IM-156 acetate

IM-156 acetate

AT36420

CAS 2043654-54-0

More details

1000 Items

$55.90

$55.90 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $36.55 Total: $182.75
110 $30.96 Total: $309.60
125 $26.23 Total: $655.75
150 $22.36 Total: $1,118.00
1100 $19.35 Total: $1,935.00

Overview

IM-156 acetate, an activator of NADH dehydrogenase (IC50=2.2 ?M) and AMP-activated protein kinase alpha (AMPK?), is an orally available and bioavailable inhibitor of mitochondrial oxidative phosphorylation (OxPhos).IM-156 acetate increases AMPK? activity and inhibits chlorhexadiene-induced peritoneal fibrosis and inhibit tumor growth in rats .

Chemical Properties

Molecular FormulaC15H20F3N5O3
Molecular Weight375.35
CAS Numbers2043654-54-0
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(O)C.FC(F)(F)OC1=CC=C(C=C1)NC(=N)NC(=N)N2CCCC2

Storage and Handling

0C Short Term, -20C Long Term

References

Izreig S, et al. Repression of LKB1 by miR-17?92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment. Cell Rep Med. 2020;1[2] 100014.