Categories
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- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $98.60 | Total: $493.00 |
| 1 | 10 | $83.52 | Total: $835.20 |
| 1 | 25 | $70.76 | Total: $1,769.00 |
| 1 | 50 | $60.32 | Total: $3,016.00 |
| 1 | 100 | $52.20 | Total: $5,220.00 |
Overview
VPC-13163 (NSC-52361) has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
Chemical Properties
| Molecular Formula | C16H14N2 |
| Molecular Weight | 234.3 |
| CAS Numbers | 6637-10-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C=1(C=2C(NC1)=CC=CC2)C3CC=4C(N3)=CC=CC4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Frederick Glenn WEST, et al. Treatment of infectious disease.WO2019183729A1