Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
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- Nuclear Receptor Ligands
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- TNF Receptors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $282.20 | Total: $1,411.00 |
| 1 | 10 | $239.04 | Total: $2,390.40 |
| 1 | 25 | $202.52 | Total: $5,063.00 |
| 1 | 50 | $172.64 | Total: $8,632.00 |
| 1 | 100 | $149.40 | Total: $14,940.01 |
Overview
Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pathogenic filamentous and dimorphic fungi such as Penicillium spp, Dermatophilus spp and Fusarium spp.
Chemical Properties
| Molecular Formula | C28H27FN6O2 |
| Molecular Weight | 498.55 |
| CAS Numbers | 1928707-56-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(NC1=CC=C(C=C1)N2CCN(CC2)C=3N=CC(F)=CN3)=O)(=O)C4=C(C=C(C)N4C)C5=CC=CC=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Mirbzadeh Ardakani E, et al. Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo. Antimicrob Agents Chemother. 2021;65[12] e0138621.