Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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- Proteins and Antibodies
- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
Ceranib1 is an inhibitor of ceramidase. It inhibits the proliferation of ovarian cancer cells. Ceranib1 inhibits ceramidase activity toward an exogenous ceramide analog, induces the accumulation of multiple ceramide species, decreases levels of S1P and sphingosine.
Chemical Properties
| Molecular Formula | C26H21NO3 |
| Molecular Weight | 395.45 |
| CAS Numbers | 328076-61-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC1=CC=C(C=CC(=O)C2=C(C3=CC=CC=C3)C3=C(NC2=O)C=CC(C)=C3)C=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Draper JM, et al. Discovery and evaluation of inhibitors of human ceramidase. Mol Cancer Ther. 2011 Nov;10[11] 2052-61.