Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $64.60 | Total: $323.00 |
| 1 | 10 | $54.72 | Total: $547.20 |
| 1 | 25 | $46.36 | Total: $1,159.00 |
| 1 | 50 | $39.52 | Total: $1,976.00 |
| 1 | 100 | $34.20 | Total: $3,420.00 |
Overview
TDRL-551 is a novel and potent replication protein A (RPA) inhibitor (IC50=18
Chemical Properties
| Molecular Formula | C25H23ClIN3O4 |
| Molecular Weight | 591.83 |
| CAS Numbers | 1644626-43-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCOc1ccc2cc(C3CC(=NN3C(=O)CCCC(O)=O)c3ccc(I)cc3)c(Cl)nc2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Mishra AK, et al. Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer. Biochem Pharmacol. 2015;93[1] 25-33.