IDE1

IDE1

AT3162

CAS 1160927-48-9

More details

1000 Items

$48.10

$48.10 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $31.45 Total: $157.25
110 $26.64 Total: $266.40
125 $22.57 Total: $564.25
150 $19.24 Total: $962.00
1100 $16.65 Total: $1,665.00

Overview

IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-? signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation.

Chemical Properties

Molecular FormulaC15H18N2O5
Molecular Weight306.31
CAS Numbers1160927-48-9
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(=NNC(CCCCCC(O)=O)=O)C1=C(C(O)=O)C=CC=C1

Storage and Handling

0C Short Term, -20C Long Term

References

Hoveizi E, et al. Definitive endoderm differentiation of human-induced pluripotent stem cells using signaling molecules and IDE1 in three-dimensional polymer scaffold. J Biomed Mater Res A. 2014 Nov;102[11] 4027-36.