Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $71.40 | Total: $357.00 |
| 1 | 10 | $60.48 | Total: $604.80 |
| 1 | 25 | $51.24 | Total: $1,281.00 |
| 1 | 50 | $43.68 | Total: $2,184.00 |
| 1 | 100 | $37.80 | Total: $3,780.00 |
Overview
MDH1-IN-2 (7c) is a potent MDH1 inhibitor with an IC50 of 2.27 ?M for MDH1 and 27.47 ?M for MDH2. MDH1-IN-2 has potential anticancer activity and can be used in the study of diseases related to the immune system.
Chemical Properties
| Molecular Formula | C25H33NO5 |
| Molecular Weight | 427.53 |
| CAS Numbers | 2143463-35-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC(=O)c1ccc(OC)c(NC(=O)COc2ccc(cc2)C(C)(C)CC(C)(C)C)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Naik R, et al. Methyl 3-[3-[4-[2,4,4-Trimethylpentan-2-yl]phenoxy]-propanamido]benzoate as a Novel and Dual Malate Dehydrogenase [MDH] 12 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60[20] 8631-8646.