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![Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine](https://img.aobious.com/img/p/5/5/2/5/3/55253-large_default.webp "Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine")
![Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine](https://img.aobious.com/img/p/5/5/2/5/3/55253.jpg "Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine")
Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine
AT62750L
CAS 2738485-99-7
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $231.20 | Total: $1,156.00 |
| 1 | 10 | $195.84 | Total: $1,958.40 |
| 1 | 25 | $165.92 | Total: $4,148.00 |
| 1 | 50 | $141.44 | Total: $7,072.00 |
| 1 | 100 | $122.40 | Total: $12,240.01 |
Overview
rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ? 0.05 ?M and an E.max value of > 250 ?M for TREM2.
Chemical Properties
| Molecular Formula | C24H23ClFN5O |
| Molecular Weight | 451.92 |
| CAS Numbers | 2738485-99-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1=NC=2C(=NC(=CC2N=C1C)[C@@H]3C[C@@H](OCC3)C4=CN(C)N=C4)C5=C(F)C=C(Cl)C=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
White RD, et al. Preparation of heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use. WO2021226629 A1.