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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Overview
CLK8 is a selective CLOCK inhibitor that binds to and interferes with CLOCK activity, disrupts the interaction between CLOCK and BMAL1, and modulates circadian rhythm amplitude.CLK8 can be used to study circadian rhythm-related disorders.
Chemical Properties
| Molecular Formula | C29H26N2O6 |
| Molecular Weight | 498.53 |
| CAS Numbers | 898920-65-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1OC2=C(C(OCC(=O)NC=3C=CC=CC3C(=O)N)=CC=4OC(C)(C)CCC42)C(=C1)C=5C=CC=CC5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Doruk YU, et al. A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude. J Biol Chem. 2020 Mar 13;295[11] 3518-3531.