Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $214.20 | Total: $1,071.00 |
| 1 | 10 | $181.44 | Total: $1,814.40 |
| 1 | 25 | $153.72 | Total: $3,843.00 |
| 1 | 50 | $131.04 | Total: $6,552.00 |
| 1 | 100 | $113.40 | Total: $11,340.01 |
Overview
H3B-8800 is an SF3B1 modulator that can be used to study transfusion-dependent anemia.
Chemical Properties
| Molecular Formula | C31H45N3O6 |
| Molecular Weight | 555.71 |
| CAS Numbers | 1825302-42-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C(=O)N1CCN(C)CC1)[C@H]2C=C[C@H](C)[C@@H](C(=CC=C[C@@H](C)C3=CC=CC=N3)C)OC(=O)C[C@H](O)CC[C@@]2(C)O |
Storage and Handling
0C Short Term, -20C Long Term
References
Rioux N, et al. Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans. Xenobiotica. 2020;50[9] 1101-1114.