Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
Overview
PF 06446846 is a potent and selective PCSK9 inhibitor
Chemical Properties
| Molecular Formula | C22H20ClN7O |
| Molecular Weight | 433.89 |
| CAS Numbers | 1632250-49-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(=O)C1=CC=C(C=C1)N2C=3C(N=N2)=CC=CN3)(C4=C(Cl)C=CC=N4)[C@@H]5CCCNC5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lintner N G , Mcclure K F , Donna P , et al. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain[J]. PLoS Biology, 2017, 15[3] e2001882-.