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Overview
Amifampridine (3,4-Diaminopyridine) is primarily used to treat rare muscle diseases. It blocks potassium channel efflux in nerve terminals, increasing action potential duration, which allows Ca2+ channels to remain open longer and enhances acetylcholine release to stimulate muscles at the end plate.
Chemical Properties
| Molecular Formula | C5H7N3 |
| Molecular Weight | 109.13 |
| CAS Numbers | 54-96-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC1=C(N)C=NC=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
wikipedia