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Overview
Thioflavin T (Basic Yellow 1) is a widely used dye for visualizing and is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections.
Chemical Properties
| Molecular Formula | C17H19ClN2S |
| Molecular Weight | 318.86 |
| CAS Numbers | 2390-54-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [Cl-].CN(C)c1ccc(cc1)-c1sc2cc(C)ccc2[n+]1C |
Storage and Handling
0C Short Term, -20C Long Term
References
Khurana R, et al. Mechanism of thioflavin T binding to amyloid fibrils. J Struct Biol. 2005 Sep;151[3] 229-38.