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Overview
Fmoc-Gly-Gly-OH, a cleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).
Chemical Properties
| Molecular Formula | C19H18N2O5 |
| Molecular Weight | 354.36 |
| CAS Numbers | 35665-38-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16[5] 315-337.