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Overview
Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.
Chemical Properties
| Molecular Formula | C14H22N4O2 |
| Molecular Weight | 278.35 |
| CAS Numbers | 370-81-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(NN=C1CCCCC1)C(=O)NN=C1CCCCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Suzuki K, et al. Status spongiosus of CNS and hepatic changes induced by cuprizone [biscyclohexanone oxalyldihydrazone]. Am J Pathol. 1969 Feb;54[2] 307-25.