Categories
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Overview
cholesterol-absorption inhibitor Intermediate 2 is a potent and orally active cholesterol absorption inhibitor that reduces blood cholesterol levels.
Chemical Properties
| Molecular Formula | C31H25F2NO3 |
| Molecular Weight | 497.53 |
| CAS Numbers | 190595-65-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Fc1ccc(cc1)N1[C@@H]([C@@H](CCC(=O)c2ccc(F)cc2)C1=O)c1ccc(OCc2ccccc2)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Rosenblum SB, et al. Discovery of 1-[4-fluorophenyl]-[3R]-[3-[4-fluorophenyl]-[3S]-hydroxypropyl]-[4S]-[4 -hydroxyphenyl]-2-azetidinone [SCH 58235] a designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem. 1998 ; 41[6] 973-980.