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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $85.00 | Total: $425.00 |
| 1 | 10 | $72.00 | Total: $720.00 |
| 1 | 25 | $61.00 | Total: $1,525.00 |
| 1 | 50 | $52.00 | Total: $2,600.00 |
| 1 | 100 | $45.00 | Total: $4,500.00 |
Overview
BI-2852 is a KRAS inhibitor targeting the switch III pocket (SIII-pocket) with nanomolar affinity, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
Chemical Properties
| Molecular Formula | C31H28N6O2 |
| Molecular Weight | 516.59 |
| CAS Numbers | 2375482-51-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cn1cnc(Cn2ccc3ccc(CNCc4[nH]c5ccccc5c4[C@H]4NC(=O)c5ccc(O)cc45)cc23)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Kessler D, et al. Drugging an undruggable pocket on KRAS. Proc Natl Acad Sci U S A. 2019 Aug 6; 116[32] 15823-15829.