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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $192.10 | Total: $960.50 |
| 1 | 10 | $162.72 | Total: $1,627.20 |
| 1 | 25 | $137.86 | Total: $3,446.50 |
| 1 | 50 | $117.52 | Total: $5,876.00 |
| 1 | 100 | $101.70 | Total: $10,170.00 |
Overview
AZD4747 is a selective and potent inhibitor of the mutant GTPase KRASG12C that crosses the blood-brain barrier and has potential antitumor activity for the study of pancreatic and colorectal adenocarcinoma.
Chemical Properties
| Molecular Formula | C24H22ClFN2O3 |
| Molecular Weight | 440.89 |
| CAS Numbers | 2489226-14-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C=C)N1CCN2CC3=CC(C#CC)=C(C(F)=C3OCC2C1)C=4C(Cl)=CC=CC4O |
Storage and Handling
0C Short Term, -20C Long Term
References
Kettle JG, et al. Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration. J Med Chem. 2023 Jul 13;66[13] 9147-9160.