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Slingshot inhibitor D3
AOB0223
CAS No: 1715076-35-9
Chemical Name: (Z)-4-((4-((4-Oxo-2-thioxo-3-(o-tolyl)thiazolidin-5-ylidene)methyl)phenoxy)methyl)benzoic acid
385 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Novel Potent Inhibitor of the Protein Phosphatase Slingshot
Chemical Properties
| Molecular Formula | C25H19NO4S2 |
| Molecular Weight | 461.55 |
| CAS Numbers | 1715076-35-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (Z)-4-((4-((4-Oxo-2-thioxo-3-(o-tolyl)thiazolidin-5-ylidene)methyl)phenoxy)methyl)benzoic acid |
| InChl Key | JZFBPGPPIJBVMI-HMAPJEAMSA-N |
| InChl Code | InChI=1S/C25H19NO4S2/c1-16-4-2-3-5-21(16)26-23(27)22(32-25(26)31)14-17-8-12-20(13-9-17)30-15-18-6-10-19(11-7-18)24(28)29/h2-14H,15H2,1H3,(H,28,29)/b22-14- |
| SMILES Code | O=C(O)C1=CC=C(COC2=CC=C(/C=C(SC(N3C4=CC=CC=C4C)=S)/C3=O)C=C2)C=C1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Lee SY, Kim W, Lee YG, Kang HJ, Lee SH, Park SY, Min JK, Lee SR, Chung SJ. Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis. Pharmacol Res. 2017 May;119:422-430. doi: 10.1016/j.phrs.2017.03.003. Epub 2017 Mar 6. PubMed PMID: 28274853.
2) Bao Z, Han X, Chen F, Jia X, Zhao J, Zhang C, Yong C, Tian S, Zhou X, Han L. Evidence for the involvement of cofilin in Aspergillus fumigatus internalization into type II alveolar epithelial cells. BMC Microbiol. 2015 Aug 13;15:161. doi: 10.1186/s12866-015-0500-y. PubMed PMID: 26268695; PubMed Central PMCID: PMC4542120.
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