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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $79.05 | Total: $395.25 |
| 1 | 10 | $66.96 | Total: $669.60 |
| 1 | 25 | $56.73 | Total: $1,418.25 |
| 1 | 50 | $48.36 | Total: $2,418.00 |
| 1 | 100 | $41.85 | Total: $4,185.00 |
Overview
Mofarotene (Ro-40-8757) is a small molecule compound that shows considerable antitumor activity in many cancer cell lines and can be used for the treatment of tumors and respiratory diseases.Mofarotene is a retinoic acid analog that binds to and activates retinoic acid receptors (RARs), which alters the expression of certain genes, leading to reduced cell differentiation and cell proliferation in susceptible cells.
Chemical Properties
| Molecular Formula | C29H39NO2 |
| Molecular Weight | 433.63 |
| CAS Numbers | 125533-88-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1(C)C=2C(C(C)(C)CC1)=CC=C(C(=CC3=CC=C(OCCN4CCOCC4)C=C3)C)C2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Valles B, et al. Metabolism of mofarotene in hepatocytes and liver microsomes from different species. Comparison with in vivo data and evaluation of the cytochrome P450 isoenzymes involved in human biotransformation. Drug Metab Dispos. 1995;23[10] 1051-1057.