Categories
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- Protein Control Ligand
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Overview
Acriflavine (Acriflavinium chloride 3,6-Acridinediamine mix) is a papain-like protease (PL(pro)) inhibitor, a fluorescent dye for labeling high molecular weight RNAs, has antimicrobial and anticancer activity, inhibits SARS-CoV-2 and other ?-coronaviruses, and can be used for research on leukemia. be used to study leukemia.
Chemical Properties
| Molecular Formula | C27H25ClN6 |
| Molecular Weight | 468.98 |
| CAS Numbers | 8048-52-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [Cl-].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]1c2cc(N)ccc2cc2ccc(N)cc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lee CJ,et al. Antitumor activity of acriflavine in lung adenocarcinoma cell line A549. Anticancer Res. 2014 Nov;34[11] 6467-72.