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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $110.50 | Total: $552.50 |
| 1 | 10 | $93.60 | Total: $936.00 |
| 1 | 25 | $79.30 | Total: $1,982.50 |
| 1 | 50 | $67.60 | Total: $3,380.00 |
| 1 | 100 | $58.50 | Total: $5,850.00 |
Overview
Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT23.
Chemical Properties
| Molecular Formula | C13H13ClN2O |
| Molecular Weight | 248.71 |
| CAS Numbers | 848193-68-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC(=O)[C@H]1CCCc2c1[nH]c1ccc(Cl)cc21 |
Storage and Handling
0C Short Term, -20C Long Term
References
Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48[25] 8045-54.