Categories
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- Protein Control Ligand
- Pathway Inhibitors
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- Nuclear Receptor Ligands
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.10 | Total: $535.50 |
| 1 | 10 | $90.72 | Total: $907.20 |
| 1 | 25 | $76.86 | Total: $1,921.50 |
| 1 | 50 | $65.52 | Total: $3,276.00 |
| 1 | 100 | $56.70 | Total: $5,670.00 |
Overview
SIRT5 inhibitor 1 is a potent and selective inhibitor of human Sirtuin 5 deacylase (IC50: 0.11 ?M) and is associated with aging-related diseases.
Chemical Properties
| Molecular Formula | C31H39FN6O6S2 |
| Molecular Weight | 674.81 |
| CAS Numbers | 2166487-21-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)CCNC(=S)NCCCC[C@H](NS(=O)(=O)c1cccc(F)c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC1CCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 ; 56[47] 14836-14841.