Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $46.75 | Total: $233.75 |
| 1 | 10 | $39.60 | Total: $396.00 |
| 1 | 25 | $33.55 | Total: $838.75 |
| 1 | 50 | $28.60 | Total: $1,430.00 |
| 1 | 100 | $24.75 | Total: $2,475.00 |
Overview
AGK7 is an inactive control of AGK2, a selective SIRT2 inhibitor that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC50 = >5 ?M, >50 ?M and >50 ?M for SIRT3, SIRT1, and SIRT2, respectively).
Chemical Properties
| Molecular Formula | C23H13Cl2N3O2 |
| Molecular Weight | 434.27 |
| CAS Numbers | 304896-21-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | ClC1=CC=C(Cl)C(=C1)C1=CC=C(O1)C=C(C#N)C(=O)NC1=C2N=CC=CC2=CC=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Tiago Fleming Outeiro, et al.Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.Science. 2007 Jul 27;317[5837] 516-9.