AK-7

AK-7

AT5490

CAS 420831-40-9

More details

1000 Items

$33.80

$33.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $22.10 Total: $110.50
110 $18.72 Total: $187.20
125 $15.86 Total: $396.50
150 $13.52 Total: $676.00
1100 $11.70 Total: $1,170.00

Overview

AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 ?M.

Chemical Properties

Molecular FormulaC19H21BrN2O3S
Molecular Weight437.35
CAS Numbers420831-40-9
SolubilityDMSO
Purity98% by HPLC
SMILES CodeBrc1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1

Storage and Handling

0C Short Term, -20C Long Term

References

Taylor DM, et al. A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylase. ACS Chem Biol. 2011 Jun 17;6[6] 540-6.