Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
ADU-S100
AOB37875
CAS: 1638750-95-4 (free acid: 1638241-89-0)
Chemical Name: MIW815; NVP-MIW815; (Rp,Rp)-2'3'-c-di-AM(PS)2 bis-sodium salt; (2',3')-Rp,Rpc-diAMPS disodium
998 Items
Overview
Novel Cyclic Dinucleotide Agonist of STING (Stimulator of Interferon Genes) pathway
Chemical Properties
| Molecular Formula | C20H22N10Na2O10P2S2 |
| Molecular Weight | 734.50 |
| CAS Numbers | 1638750-95-4 (sodium) |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (2',3')-Rp,Rpc-diAMPS disodium |
| InChl Key | GDWOOOCBNOMMTL-ITQXCAEYSA-L |
| InChl Code | InChI=1S/C20H24N10O10P2S2.2Na/c21-15-9-17(25-3-23-15)29(5-27-9)19-12(32)13-8(38-19)2-36-42(34,44)40-14-11(31)7(1-35-41(33,43)39-13)37-20(14)30-6-28-10-16(22)24-4-26-18(10)30;;/h3-8,11-14,19-20,31-32H,1-2H2,(H,33,43)(H,34,44)(H2,21,23,25)(H2,22,24,26);;/q;2*+1/p-2/t7-,8-,11-,12-,13-,14-,19-,20-,41-,42-;;/m1../s1 |
| SMILES Code | O[C@@H]1[C@@H](CO[P@@]([S-])(O[C@H]2[C@@H](O)[C@H](N3C4=C(C(N)=NC=N4)N=C3)O[C@@H]2CO5)=O)O[C@@H](N6C7=C(C(N)=NC=N7)N=C6)[C@@H]1O[P@@]5([S-])=O.[Na+].[Na+] |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
ADU-S100; ADU S100; ADUS100; ML RR-S2 CDA sodium salt
References
1) Gountas I, et. HCV elimination among people who inject drugs. Modelling pre- and post-WHO elimination era. PLoS One. 2018 Aug 16;13(8):e0202109.
2) Razavi-Shearer D, Razavi H. Global prevalence of hepatitis B virus infection and prevention of mother-to-child transmission - Authors' reply. Lancet Gastroenterol Hepatol. 2018 Sep;3(9):599.
3) Vakharia PP, Chopra R, Silverberg NB, Silverberg JI. Efficacy and Safety of Topical Cantharidin Treatment for Molluscum Contagiosum and Warts: A Systematic Review. Am J Clin Dermatol. 2018 Aug 10.
